ChemicalBook > CAS DataBase List > N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
- Product Name
- N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
- CAS No.
- 103878-83-7
- Chemical Name
- N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid
- Synonyms
- TeMpiuM;Ro 19-6327/001;JMFKTFLARGGXCC-UHFFFAOYSA-N;N-(2-Aminoethyl)-5-chlor-2-pyridincarbox;N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid;N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride;2-PyridinecarboxaMide, N-(2-aMinoethyl)-5-chloro-, Monohydrochloride;ichemia,Lazabemide,DOPAC,MAO,radical generation,Ro 19-6327,disease,alzheimer′s,Inhibitor,inhibit,Lazabemide hydrochloride,Monoamine Oxidase,smoking cessation,parkinson
- CBNumber
- CB11448718
- Molecular Formula
- C8H10ClN3O.HCl
- Formula Weight
- 0
- MOL File
- 103878-83-7.mol
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N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Property
- Melting point:
- 193-195°
- storage temp.
- Desiccate at RT
- solubility
- Soluble to 100 mM in water and to 100 mM in DMSO
- form
- Powder
- pka
- 8.9(at 25℃)
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Safety
- Toxicity
- LD50 orally in mice: 1000-2000 mg/kg (Imhof, Kyburz, 1986)
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N-Bromosuccinimide Price
TRC
- Product number
- L215258
- Product name
- LazabemideHydrochloride
- Packaging
- 50mg
- Price
- $305
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0003133
- Product name
- LAZABEMIDE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $648.83
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B7064
- Product name
- Lazabemidehydrochloride
- Packaging
- 50mg
- Price
- $795
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0003133
- Product name
- LAZABEMIDE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $976.27
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B7064
- Product name
- Lazabemidehydrochloride
- Packaging
- 10mg
- Price
- $196
- Updated
- 2021/12/16
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N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Chemical Properties,Usage,Production
Uses
Treatment of Alzheimer’s disease.
Uses
Lazabemide Hydrochloride is a reversible and selective inhibitor of MAO-A and MAO-B, both of which oxidatively deaminate neurotransmitter and xenobiotic amines.
Definition
ChEBI: Lazabemide hydrochloride is a pyridinecarboxamide.
brand name
Tempium (Hoffmann-LaRoche).
Biological Activity
Selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC 50 values are 0.03 and > 100 μ M for MAO-B and MAO-A respectively). Inhibits monoamine uptake at high concentrations (IC 50 values are 86, 123 and > 500 μ M for noradrenalin, serotonin and dopamine uptake respectively).
storage
Desiccate at RT
N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Preparation Products And Raw materials
Raw materials
Preparation Products
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N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid Suppliers
- Tel
- +1-833-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 57511
- Advantage
- 58
- Tel
- +1-781-999-5354
- support@targetmol.com
- Country
- United States
- ProdList
- 19973
- Advantage
- 58
103878-83-7, N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochloridRelated Search:
Methylamine hydrochloride
Cysteamine hydrochloride
1-(5-CHLOROPYRIDIN-2-YL)METHANAMINE
METHYLPYRIDIN-2-YLMETHYLAMINE DIHYDROCHLORIDE
5-CHLORO-2-FORMYLPYRIDINE
LAZABEMIDE
5-Chloropyridine-2-carboxamide
PYRIDINE-2-CARBOXYLIC ACID (2-AMINO-ETHYL)-AMIDE
N-(2-Aminoethyl)-5-chlor-2-pyridincarboxamid-hydrochlorid